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The California State University


  • Crowhurst, K.A. and S.L. Mayo. 2008. NMR-detected conformational exchange observed in a computationally designed variant of protein Gbeta1. Protein Engineering, Design and Selection 21: 577-587.

  • Neale, C., J.A. Marsh, F.E. Jack, W. Choy, A. Lee and K.A. Crowhurst. 2007. Improved structural characterization of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure. Journal of Molecular Biology 367: 1494-1510.

  • Shah, P.S., G.K. Hom, S.A. Ross, J.K. Lassila, K.A. Crowhurst and S.L. Mayo. 2007. Full-sequence computational design and solution structure of a thermostable protein variant. Journal of Molecular Biology 372: 1-6.

  • Crowhurst, K.A., W. Choy, Y. Mok and J.D. Forman-Kay. 2003. Corrigendum to the paper by Mok et al (1999) NOE data demonstrating a compact unfolded state for an SH3 domain under non-denaturing conditions. Journal of Molecular Biology 329: 185-187.

  • Tollinger, M., K.A. Crowhurst, L.E. Kay and J.D. Forman-Kay. 2003. Site-specific contributions to the pH dependence of protein stability. Proceedings of the National Academy of Sciences of the United States of America 100: 4545-4550.

  • Crowhurst, K.A. and J.D. Forman-Kay. 2003. Aromatic and methyl NOEs highlight hydrophobic clustering in the unfolded state of an SH3 domain. Biochemistry-US 42: 8687-8695.

  • Choy, W., F.A. Mulder, K.A. Crowhurst, D.R. Muhandiram, I.S. Millett, S. Doniach, J.D. Forman-Kay and L.E. Kay. 2002. Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques. Journal of Molecular Biology 316: 101-112.

  • Crowhurst, K.A., M. Tollinger and J.D. Forman-Kay. 2002. Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain. Journal of Molecular Biology 322: 163-178.

  • Woolley, G.A., P.C. Biggin, A. Schultz, L. Lien, D.C. Jaikaran, J. Breed, K. Crowhurst and M.S. Sansom. 1997. Intrinsic rectification of ion flux in alamethicin channels: Studies with an alamethicin dimer. Biophysical Journal 73: 770-778.

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Educational Background

  • 2003 – PhD, University of Toronto (Biochemistry)

  • 1997 – MSc, University of Toronto (Chemistry)

  • 1995 – BSc (Honours), Queen's University (Chemistry)

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  • Faculty-Student Collaborative Research Seed Grant

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Positions & Honors

  • 2004 – Postdoctoral Fellowship, Natural Sciences and Engineering Research Council of Canada (NSERC)

  • 2003 – Elizabeth Ross Postdoctoral Fellowship, California Institute of Technology

  • 2000 – Doctoral Research Award, Canadian Institutes of Health Research (CIHR)

  • 1995 – Graduate Fellowship, Canadian Cystic Fibrosis Foundation

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