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The California State University

Publications

  • Upton, K.R. and L.G. Riley. Forthcoming. Acute stress inhibits food intake and alters ghrelin signaling in the brain of tilapia (Oreochromis mossambicus). Domestic Animal Endocrinology.

  • Riley, L.G. 2013. Different forms of ghrelin exhibit distinct biological roles in tilapia: mini review. Frontiers in Endocrinology 118.

  • Janzen, W.J., C.A. Duncan and L.G. Riley. 2012. Cortisol treatment reduces ghrelin signaling and food intake in tilapia, Oreochromis mossambicus. Domestic Animal Endocrinology 43: 251-259.

  • Peterson, B.C., G.C. Waldbieser, L.G. Riley, K.R. Upton, Y. Kobayashi and B.C. Small. 2012. Pre- and postprandial changes in orexigenic and anorexigenic factors in channel catfish (Ictalurus punctatus). General and Comparative Endocrinology 176: 231-239.

  • Schwandt, S.E., S. Peddu and L.G. Riley. 2010. Differential roles for octanoylated and decanoylated ghrelins in regulating appetite and metabolism. Int. J. Peptides doi:10.1155/2010/275804.

  • Kaiya, H., L. Riley, W. Janzen, T. Hirano, E. Grau, M. Miyazato and K. Kangawa. 2009. Identification and Genomic Sequence of a Ghrelin Receptor (GHS-R)-like Receptor in the Mozambique Tilapia, Oreochromis mossambicus. Zoological Science (Tokyo) 26: 330-337.

  • Peddu, S., J. Breves, H. Kaiya, E. Grau and L. Riley. 2009. Pre- and postprandial effects on ghrelin signaling in the brain and on the GH/IGF-I axis in the Mozambique tilapia (Oreochromis mossambicus). General and Comparative Endocrinology 161: 412-418.

  • Picha, M., C. Strom, L. Riley, A. Walker, E. Won, W. Johnstone and R. Borski. 2009. Plasma ghrelin and growth hormone regulation in response to metabolic state in hybrid striped bass. General and Comparative Endocrinology 161: 365-372.

  • Davis, L., N. Visitacion, L. Riley, N. Hiramatsu, C. Sullivan, T. Hirano and E. Grau. 2009. Effects of o,p '-DDE, heptachlor, and 17 beta-estradiol on vitellogenin gene expression and the growth hormone/insulin-like growth factor-I axis in the tilapia, Oreochromis mossambicus. Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology: 507-514.

  • Riley, L., A. Walker, C. Dorough, S. Schwandt and E. Grau. 2009. Glucose regulates ghrelin, neuropeptide Y, and the GH/IGF-I axis in the tilapia, Oreochromis mossambicus. Comparative Biochemistry and Physiology Part a Molecular & Integrative Physiology 154: 541-546.

  • Riley, L., B. Fox, J. Breves, H. Kaiya, C. Dorough, T. Hirano and E. Grau. 2008. Absence of Effects of Short-Term Fasting on Plasma Ghrelin and Brain Expression of Ghrelin Receptors in the Tilapia, Oreochromis mossambicus. Zoological Science (Tokyo) 25: 821-827.

  • Fiess, J., A. Kunkel-Patterson, L. Mathias, L. Riley, P. Yancey, T. Hirano and F. Grau. 2007. Effects of environmental salinity and temperature on osmoregulatory ability, organic osmolytes, and plasma hormone profiles in the Mozambique tilapia (Oreochromis mossambicus). Comparative Biochemistry and Physiology Part a Molecular & Integrative Physiology: 252-264.

  • Fox, B., L. Riley, C. Dorough, H. Kaiya, T. Hirano and E. Grau. 2007. Effects of homologous ghrelins on the growth hormone/insulin-like growth factor-I axis in the Tilapia, Oreochromis mossambicus. Zoological Science (Tokyo) 24: 391-400.

  • Kawakoshi, A., H. Kaiya, L. Riley, T. Hirano, E. Grau, M. Miyazato, H. Hosoda and K. Kangawa. 2007. Identification of a ghrelin-like peptide in two species of shark, Sphyrna lewini and Carcharhinus melanopterus. General and Comparative Endocrinology: 259-268.

  • Fox, B.K., L.G. Riley, T. Hirano and E.G. Grau. 2006. Effects of fasting on growth hormone, growth hormone receptor and insulin-like growth factor-I axis in seawater-acclimated tilapia, Oreochromis mossambicus. Gen Comp Endocrinol 148: 340-347.

  • Shoemaker, J., L. Riley, T. Hirano, E. Grau and D. Rubin. 2006. Differential expression of tuberoinfundibular peptide 38 and glucose-6-phosphatase in tilapia. General and Comparative Endocrinology: 186-194.

  • Riley, L., B. Fox, H. Kaiya, T. Hirano and E. Grau. 2005. Long-term treatment of ghrelin stimulates feeding, fat deposition, and alters the GH/IGF-I axis in the tilapia, Oreochromis mossambicus. General and Comparative Endocrinology 142: 234-240.

  • Shepherd, B.S., G.M. Weber, M.M. Vijayan, A. Seale, L.G. Riley, N.H. Richman III, T. Hirano and E.G. Grau. 2004. Control of Growth in Tilapia: Developments and Prospects. In Tilapias: Culture, Nutrition and Feeding., edited by . Haworth Press, Inc.

  • Riley, L., T. Hirano and E. Grau. 2004. Estradiol-17β and dihydrotestosterone differentially regulate vitellogenin and insulin-like growth factor-I production in primary hepatocytes of the tilapia Oreochromis mossambicus. Comparative Biochemistry & Physiology Part C: Toxicology & Pharmacology 138: 177-186.

  • Riley, L.G., T. Hirano and E.G. Grau. 2003. Effects of transfer from seawater to fresh water on the growth hormone/insulin-like growth factor-I axis and prolactin in the tilapia, Oreochromis mossambicus. Comp Biochem Physiol B 136: 647-655.

  • Kaiya, H., M. Kojima, H. Hosoda, L.G. Riley, T. Hirano, E.G. Grau and K. Kangawa. 2003. Amidated fish grelin: purification, cDNA cloning in the Japanese eel and its biological activity. J. Endocrinnol 176: 415-423.

  • Uchida, K., S. Kajimura, L.G. Riley, T. Hirano, K. Aido and E.G. Grau. 2003. Effects of fasting on growth hormone/insulin-like growth factor I axis in the tilapia, Oreochromis mossambicus. Comp Biochem Physiol A 134: 429-439.

  • Kaiya, H., M. Kojima, H. Hosoda, L. Riley, T. Hirano, E. Grau and K. Kangawa. 2003. Identification of tilapia ghrelin and its effects on growth hormone and prolactin release in the tilapia, Oreochromis mossambicus. Comparative Biochemistry and Physiology Part B Biochemistry & Molecular Biology: 421-429.

  • Sparks, R., B. Shepherd, B. Ron, N. Richman, L. Riley, G. Iwama, T. Hirano and E. Grau. 2003. Effects of environmental salinity and 17alpha-methyltestosterone on growth and oxygen consumption in the tilapia, Oreochromis mossambicus. Comparative Biochemistry and Physiology Part B Biochemistry & Molecular Biology: 657-665.

  • Kaiya, H., M. Kojima, H. Hosoda, L.G. Riley, T. Hirano, E.G. Grau and K. Kangawa. 2002. A novel growth hormone secretagogue, ghrelin: identification and biological activity in fish. Fish Sci 68: 749-752.

  • Seale, A.P., T. Itoh, S. Moriyama, A. Takahashi, H. Kawauchi, T. Sakamoto, M. Fujimoto, L.G. Riley, T. Hirano and E.G. Grau. 2002. Isolation and characterization of a homologous prolactin-releasing peptide from the tilapia brain and its effects on prolactin release from the tilapia pituitary. Gen Comp Endocrinol 125: 328-330.

  • Riley, L.G., T. Hirano and E.G. Grau. 2002. Disparate effects of gonadal steroid hormones on plasma and liver mRNA levels of insulin-like growth factor-I and vitellogenin in the tilapia, Oreochromis mossambicus. Fish Physiol Biochem 26: 223-230.

  • Seale, A., L. Riley, T. Leedom, S. Kajimura, R. Dores, T. Hirano and E. Grau. 2002. Effects of environmental osmolality on release of prolactin, growth hormone and ACTH from the tilapia pituitary. General and Comparative Endocrinology: 91-101.

  • Riley, L., T. Hirano and E. Grau. 2002. Rat ghrelin stimulates growth hormone and prolactin release in the tilapia, Oreochromis mossambicus. Zoological Science (Tokyo): 797-800.

  • Riley, L., N. Richman, T. Hirano and E. Grau. 2002. Activation of the growth hormone/insulin-like growth factor axis by treatment with 17alpha-methyltestosterone and seawater rearing in the tilapia, Oreochromis mossambicus. General and Comparative Endocrinology: 285-292.

  • Kajimura, S., K. Uchida, T. Yada, L.G. Riley, J.C. Byatt, J.R. Collier, T. Hirano and E.G. Grau. 2001. Stimulation of insulin-like growth factor-I production by recombinant bovine growth hormone in the Euryhaline tilapia, Oreochromis mossambicus. Fish Phsiol Biochem 25: 221-230.

  • Meredith, H.O., N.H. Richman III, J.T. Collier, A.P. Seale, L.G. Riley, C.H. Ball, S.K. Shimoda, M.H. Stetson and E.G. Grau. 1999. Pesticide effects on prolactin release from the rostral pars distalis in vitro and their effects on growth in vivo in the tilapia (Oreochromis mossambicus)”. In Environmental Toxicology and Risk Assessment: Eighth volume, ASTM STP 1364, edited by D.S. Henshel, M.C. Black and M.C. Harras. West Conshohocken: American Society for Testing and Materials.

  • Riley, L.G. and B. Tsukimura. 1998. Yolk protein synthesis in the riceland tadpole shrimp, Triops Longicaudatus, measured by in vitro incorporation of 3H-leucine. J. Exp. Zool 281: 238-247.

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Educational Background

  • 2005 – Post-doc, University of Hawaii (Zoology)

  • 2003 – Ph.D., University of Hawaii (Zoology)

  • 1997 – M.S., California State University at Fresno (Biology)

  • 1995 – B.A., California State University at Fresno (Biology)

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Grants

  • Investigations into the Stress Reducing Effects of Selenium-enriched Feed in an Important Aquaculture Species, Tilapia (Oreochromis mossambicus)

  • Endocrine Control of Appetite and Growth during Stress in the Tilapia

  • Glucose Regulates Metabolic Energy Balance by Altering Ghrelin Production and the Growth Axis in the Tilapia

  • Ghrelin's Role as a Regulator of Glucose Metabolism using the Tilapia (Oreochromis mossabmicus) as a model

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Positions & Honors

  • 2009 – College of Science and Math "Best in Show", California State University at Fresno

  • 2009 – Provost "Promising Young Faculty" Award, California State University at Fresno

  • 2007-present – Faculty Coordinator - LSAMP program, California State University at Fresno

  • 2007-2010 – Chair - Student/Postdoc Advisory Committee, Society of Integrative & Comparative Biology

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